Treatment

  We spoke with Stéphane Bidet, CEO of Hillo — http://hillo.ai.   “Nicolas Caleca, CSO, and I founded this company to reduce the fear and unpredictability of managing T1D. “My wife has T1D and I see her struggles. She is…

We spoke with Mats Koeneman, MSc and Technical Physician with the REshape Center for Innovation at Radboud University Medical Center, The Netherlands — https://www.radboudumc.nl/reshape — who co-authored a recent study in Diabetes Journal to get his thoughts on how wearables…

Introduction Diabetes is such a difficult condition to manage. With changes in your food, variations in exercise, stress, illness and a myriad of other factors that seem to change at random, it can be overwhelming. The good news is that…

We spoke with Ulrike Schierloh, MD who is with the Pediatric Clinic, Centre Hospitalier de Luxembourg, Luxembourg, GD de Luxembourg about the study that was just published in PLOS|One. Study Overview This study obtained glucose levels as well as plasma…

Many people with diabetes have developed a love-hate relationship with insulin. This life-saving, wallet-shrinking, high-fixing, low-causing, pain-to-dose wonder molecule is a mainstay of diabetes care. There are many flavors of insulin out there so let’s start by breaking down the…

We spoke with Cyndi Williams, Co-Founder and CEO of Quin — https://quintech.io — about their Insulin Intervention Taxonomy and how these data sets produce better T1D insulin dosing recommendations. Quin believes that self-care T1D insulin-dosing strategies derived from each individual’s…

Carbohydrate counting (or carb counting) is a traditional method for mealtime insulin dosing. It utilizes insulin to carb ratios for calculating meal doses. The Insulin-Carb ratio has been taught for years and is a decent method for dosing insulin based…

“Closed-loop insulin pump therapy is the most exciting new development in type 1 diabetes in decades because it acts as an artificial pancreas,” said co-lead investigator Gregory Goodwin, M.D., a senior associate physician in medicine at Boston Children’s Hospital in…

The FDA declined to approve Zynquista a drug developed by Sanofi SA and Lexicon Pharmaceuticals intended for use with insulin in patients with Type 1 Diabetes.  The generic name of the drug is sotagliflozin. The decision comes about two months after…

We spoke with Marc Rippen, co-founder and President of Alertgy, a startup founded in 2016 and based in Melbourne, Florida.  Marc and his team have strong backgrounds in the defense industry and are applying expertise to CGMs that was developed…

The U.S. Food and Drug Administration says the Tandem Diabetes Care t:slim X2™ insulin pump now has an interoperable designation. “Diabetes is a complicated disease that requires close monitoring and carefully tailored treatments. We’ve heard from the patient community that…

We spoke with PKvitality’s General Manager Minh Lê, and CGM consultant Tom Bishop. They shared their investor slide deck and we have included selected images in this article. CGM Reimagined The PKvitality team wants to disrupt the existing CGM market.…

This article was written with a lot of help from Brad, a clinical pharmacist and pharmacotherapy specialist working in a hospital with a practice focus on diabetes.  Brad is also a T1Dad to an amazing 3rd grader. Why Understanding SGLT2…

In 2018, JDRF celebrated the first anniversary of its Open Protocol initiative to support the development of automated insulin delivery systems, including artificial pancreas (AP) algorithms, continuous glucose monitors (CGM) and insulin pumps.  The goal is to increase the ability…

Michael is a pharmacist by training and a turnaround expert with a strong record of healthcare innovation.  He described the progress that MannKind has made since he joined the company in 2016. MannKind describes themselves a biopharmaceutical company that focuses…

Modeling Food to Glucose Process Many physiologic processes in the body have been described with a model-based structure. Insulin absorption was modeled as early as 1959, and compartment models for it followed. Insulin’s effect on glucose was modeled with compartment…

Diabetes care is especially complex for T2D because there are a lot of variables that impact the effect of food, insulin, and exercise on blood glucose. Fortunately for Type 1 diabetes, the body’s food and insulin inputs, and the resulting…

How to interpret CGM for BG control Continuous glucose monitors provide a wealth of information that may be used tactically to improve BG control.  Some of this is provided right on a Dexcom CGM receiver by the “trend arrow” that…

Bolus insulin is the insulin you take for food What you eat is digested in stages; some is absorbed right in the mouth, which is what makes honey the best thing to use for a serious hypoglycemic emergency.  Honey is…

Glucose measurement technology has advanced and this has enabled the control strategies that can be used today. Introduction Our body needs the energy to work, and there are just a few ways for cells to get that energy: oxidizing (burning)…