Research

New Vaccine Targets 6 Viruses that May Cause Type 1 Diabetes

New Vaccine Targets 6 Viruses that May Cause Type 1 Diabetes

A new vaccine developed by Finnish and Swedish researchers that targets six strains of enterovirus and could have a profound impact on the rates of type 1 diabetes. The viruses in question all belong to the Coxsackie B (CVB) subgroup.…
Are Gluten-Free Diets Good for Everyone?

Are Gluten-Free Diets Good for Everyone?

People with type 1 diabetes are at an increased risk for developing a number of other autoimmune disorders, including celiac disease. In fact, while celiac occurs in the general population at a rate of about 0.5%, it is seen in…
Insulin’s Role in Vascular Damage

Insulin’s Role in Vascular Damage

Cardiovascular disease is the number one killer of people living with long term type 1 diabetes.  This remains true despite huge advancements in blood sugar management technology, more effective insulins, and an increased focus on heart health. The risk of…
New Study Questions Rotavirus Vaccine Effect on T1D Development

New Study Questions Rotavirus Vaccine Effect on T1D Development

Excitement over a potential preventative treatment for type 1 diabetes reached a high last year as multiple studies showed a link between inoculation with the rotavirus vaccine and a reduced rate of T1D development in children. These studies came after…
Free Type 1 Diabetes Screening for Children Saves Lives and Aids Research

Free Type 1 Diabetes Screening for Children Saves Lives and Aids Research

As a parent living with type 1 diabetes, it is impossible for me to watch my child vacuum up a meal or gulp down a glass of water without getting worried. Even something as simple as an extra heavy diaper…
Deleting Gene in Mice Prevents T1D from Developing

Deleting Gene in Mice Prevents T1D from Developing

Researchers at the University of Wisconsin-Madison made a surprising discovery recently when they deleted the IRE1-alpha gene in mice destined to develop type 1 diabetes. Deleting this gene caused the beta cells in the mice to de-differentiate or revert to…
Possible T1D Treatment Shows Promise to Reduce COVID-19 Complications

Possible T1D Treatment Shows Promise to Reduce COVID-19 Complications

I spoke with Dr. Denise Faustman about her upcoming trial to test the effectiveness of the BCG vaccine to protect high-risk healthcare workers from COVID-19 complications Last year we had the opportunity to talk with Dr. Faustman, an Associate Professor…
Should We Be Excited About ‘Curing’ T1D in Mice?

Should We Be Excited About ‘Curing’ T1D in Mice?

You have probably already heard the exciting news out of the Washington University School of Medicine in St. Louis.  Researchers there have successfully implanted stem cells in mice to ‘cure’ their diabetes. As exciting as this news seems, it is…
Why T1D Diagnosis Rates Continue to Rise Across the Globe

Why T1D Diagnosis Rates Continue to Rise Across the Globe

The prevalence of type 1 diabetes was relatively stable for much of human history until the second half of the 20th century. But something very strange began to happen around 1950. Suddenly, the rate of type 1 diabetes, especially in…
Glucagon Patch Promises to Stop Low Blood Sugars Before They Happen

Glucagon Patch Promises to Stop Low Blood Sugars Before They Happen

When it comes to managing type 1 diabetes, there is one item that is central to every aspect of the condition: Insulin. This simple, yet necessary hormone has transformed what was once a sure death sentence into a condition that…
Insulin Patch Could Provide Cheap, Simple, and Effective “Cure” for T1D

Insulin Patch Could Provide Cheap, Simple, and Effective “Cure” for T1D

When you picture the future of type 1 diabetes treatment, what comes to mind? For many, they see high tech devices capable of reading blood glucose levels and adjusting insulin and glucagon rates to keep sugars stable. Others see stem…
Will ViaCyte’s Encaptra Cell Delivery System ‘Cure’ Type 1 Diabetes?

Will ViaCyte’s Encaptra Cell Delivery System ‘Cure’ Type 1 Diabetes?

When you were diagnosed with type 1 diabetes, you were probably told that a cure was “just around the corner.” And that “corner” likely came and went years or decades ago. While a true cure isn’t exactly just a few…
Heart Disease Risk Is Greatest in Women with Type 1 Diabetes

Heart Disease Risk Is Greatest in Women with Type 1 Diabetes

Heart disease kills more people in the developed world than any other condition. In America, about 1 in 5 women will die of heart disease while men succumb to the disease at a rate of about 1 in 4. Despite…
New Biotechnology Promises to “Cure” Type 1 Diabetes Within 5 Years

New Biotechnology Promises to “Cure” Type 1 Diabetes Within 5 Years

A team of medical researchers and several Nobel Prize winners from Betalin Therapeutics in Jerusalem has created a “bio-artificial pancreas” made from — wait for it — pig lung tissue and beta-cells.  How it works The “biological pancreas” is implanted…
Rating the Performance of Popular Diabetes Non-Profits

Rating the Performance of Popular Diabetes Non-Profits

Many in the Type 1 Diabetes community want to work for a cure, but philanthropy is the way most of us can help fund new treatments and cure research. Some charity dollars go further than others, and donors want to…
IFNα Kinoid: A promising vaccine against Type 1 Diabetes

IFNα Kinoid: A promising vaccine against Type 1 Diabetes

Neovacs — www.neovacs.fr — is a French biotech company focused on the development of Kinoids®, therapeutic vaccines for the treatment of autoimmune, inflammatory diseases, allergies, and cancer.  They presented pre-clinical results for T1D its therapeutic vaccine, IFNα Kinoid, during an…
Blood glucose-dependent insulin delivery to simplify treatment

Blood glucose-dependent insulin delivery to simplify treatment

We corresponded with Jingqiang Wang and Professor Zhen Gu of UCLA Engineering about their research on glucose-responsive insulin analogs (ref). The goal of their research is a simple-to-administer system that delivers insulin in a blood glucose-dependent manner. Q1: Is subcutaneous…
Metformin improves insulin sensitivity in overweight/obese adolescents with T1D

Metformin improves insulin sensitivity in overweight/obese adolescents with T1D

We spoke with Kristen Nadeau, MD, MS, (bio) Professor of Pediatrics and Research Director, Pediatric Endocrinology at the University of Colorado SOM about a study that was just published in The Journal of Clinical Endocrinology & Metabolism. Context “Type 1…
Diasome’s Liver Targeted Insulin

Diasome’s Liver Targeted Insulin

We spoke with Robert Geho, CEO of Diasome Pharmaceuticals, Inc. — www.diasome.com — about its nanotechnology additive that delivers insulin to the liver where it can substantially improve T1D glucose control. Normal vs Injected Insulin In normal human physiology, the…
Aaron Kowalski Appointed New JDRF President/CEO

Aaron Kowalski Appointed New JDRF President/CEO

Today, the JDRF announced the appointment of Aaron J. Kowalski, Ph.D., as the nonprofit’s President and Chief Executive Officer. A 15-year veteran of JDRF and the first person living with T1D to lead the research organization, Dr. Kowalski has a…
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