David Worthington

I was well established in my engineering career in 1984 when, at age 39, I came down with Type 1 Diabetes (T1D). I was always technically inclined, and majored in physics in college, then did graduate work in Cybernetic Systems. My focus was on engineering control systems, including adaptive control and model-based control, as opposed to traditional feedback control.
Living

FDA’s rejection of SGLT for T1D

SGLT2 Development and Method of Action Ever since the first SGLT2 inhibitor (dapagliflozin) was approved by the EU in 2011…

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Living

Report on Digital Diabetes Congress

This two-day event, on May 14-15, 2019, was first announced on January 18, 2019, with a mobile app contest, whose…

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Treatment

Food Effect on Glucose

Modeling Food to Glucose Process Many physiologic processes in the body have been described with a model-based structure. Insulin absorption…

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Treatment

A Systems Approach to T1D Care

Diabetes care is especially complex for T2D because there are a lot of variables that impact the effect of food,…

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Treatment

Using CGMs, Insulin Pens, and Pumps

How to interpret CGM for BG control Continuous glucose monitors provide a wealth of information that may be used tactically…

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Treatment

Bolus Insulin Management in T1D

Bolus insulin is the insulin you take for food What you eat is digested in stages; some is absorbed right…

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Treatment

Physiology of Managing T1D

Glucose measurement technology has advanced and this has enabled the control strategies that can be used today. Introduction Our body…

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Treatment

Acronyms and References

Acronyms and References   amylin https://en.wikipedia.org/wiki/Amylin AndriodAPS https://androidaps.readthedocs.io/en/latest/EN/ Aspart https://en.wikipedia.org/wiki/Insulin_aspart Automated insulin delivery https://diatribe.org/automated-insulin-delivery BG (Blood Glucose) https://en.wikipedia.org/wiki/Blood_sugar_level blood plasma…

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Treatment

Basal insulin Management in T1D

Overview The current insulin regimen for glucose management is called basal-bolus, named after its two components: Basal—background insulin reflecting second…

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Treatment

My T1D Journey as a Systems Engineer

Systems Education I was always technically inclined, and majored in physics in college, then did graduate work in Cybernetic Systems.…

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