Research

Regrowth of Human Beta Cells for T1D and T2D

Regrowth of Human Beta Cells for T1D and T2D

Effective Therapeutic Rate A combination of two drugs enhances the production of beta cells such that they proliferate at the highest rate ever observed in humans – a rate of 5 to 8 percent per day. “Beta cell regeneration is…
Understanding Pancreas Cell Development

Understanding Pancreas Cell Development

Prof. Dr. Henrik Semb who led the study explains his recent paper in Nature. Dr. Semb and his team have discovered the signals that determine the fate of immature cells in the pancreas. The research shows that they are very…
Seraxis Islet Technology Aims for Practical T1D Cure

Seraxis Islet Technology Aims for Practical T1D Cure

Islet transplants offer the hope of a permanent cure for Type 1 Diabetes.  After nearly six years in stealth mode, Seraxis has emerged as a front-runner in the race to clinical islet deployment.  Privately funded, and without any NIH or…
Leveraging T2D Drugs to improve T1D Therapy

Leveraging T2D Drugs to improve T1D Therapy

Paresh Dandona, MD, Ph.D. (bio) has been passionate about blood sugar control since he became a Fellow in London in 1975.  He joined the faculty of the University of Buffalo School of Medicine in 1995 and has a remarkable track…
Pramlintide Reimagined and Results are Promising

Pramlintide Reimagined and Results are Promising

Over a decade ago, the US approval and launch of pramlintide (Symlin® AstraZeneca) brought a lot of excitement because of its therapeutic ability, when used in combination with mealtime insulin, to flatten post-meal blood glucose levels, reduce glucose excursions, and…
Could bacteria be causing diabetes?

Could bacteria be causing diabetes?

The relationship between gut bacteria, genetics, and T1D risk is a complicated picture, but multiple studies indicate that gut bacteria is an essential factor. TEDDY The Environmental Determinants of Diabetes in the Young (TEDDY) is on ongoing, multi-study effort that…
Metformin May Improve Vascular Health in T1D Adolescents

Metformin May Improve Vascular Health in T1D Adolescents

Cardio vascular disease is the leading cause of mortality in people with T1D.   This relates strongly to insulin resistance and both lean and obese T1D adolescents have marked insulin resistance. Metformin is known to improve surrogate markers of insulin resistance…
Update on Inhaled Insulin

Update on Inhaled Insulin

Rapid-acting insulins such as Novolog and Humalog often show peak insulin levels up to 3 hours after injection.  In this period, glucose levels may fluctuate considerably.  Inhaled insulin starts working more quickly and peaks in less than one hour. Diabetes…
Race to introduce a T1D drug that inhibits glucose absorption

Race to introduce a T1D drug that inhibits glucose absorption

Sodium-glucose co-transporter 2 (SGLT2) inhibitors, also called gliflozin drugs, are a new class of diabetic medications. They work by reducing the re-absorption of glucose into the blood via the kidneys with the excess glucose urinated. The FDA has already approved…
Insulin could be a Possible New Therapy for Colitis

Insulin could be a Possible New Therapy for Colitis

Insulin is widely used to treat diabetes, and it may be beneficial in treating other conditions.
Maternal Gluten Intake Linked to T1D in Children

Maternal Gluten Intake Linked to T1D in Children

A study in Denmark covering more than 67,000 pregnancies mothers has revealed that mothers that consumed 20 g/day of gluten had double the risk of T1D development in their offspring!
New predictors are a lifeline for families living with Type 1 Diabetes

New predictors are a lifeline for families living with Type 1 Diabetes

Combining genetic testing with existing NIH TrialNet procedures has shown very positive initial results in predicting T1D.*
New Type 1 Therapy Promises Long-term Diabetes Reversal in Humans and Dogs

New Type 1 Therapy Promises Long-term Diabetes Reversal in Humans and Dogs

Preclinical animal study shows initial results on the first minimally invasive therapy to successfully reverse Type 1 diabetes within 24 hours and maintain insulin independence for at least 90 days.
JDRF To Help Study Hypoglycemia

JDRF To Help Study Hypoglycemia

JDRF announces plans to participate in Hypo-RESOLVE research project.
Diabetes as a Disability in the Workplace

Diabetes as a Disability in the Workplace

An expert clarifies the laws that impact diabetes in the workplace.
How to Evaluate Diets and Supplements

How to Evaluate Diets and Supplements

A nutrition expert offers tips for thinking critically about health and weight loss claims.
Country Music Star Says She Was Harassed for Diabetic Service Dog

Country Music Star Says She Was Harassed for Diabetic Service Dog

RaeLynn was on her way to a diabetes conference when she encountered a suspicious flight attendant.
Mini-Glucagon With Alcohol?

Mini-Glucagon With Alcohol?

Danish study suggests that a low dose of glucagon may help T1Ds prone to hypoglycemia after alcohol.
CDC Report Understates Link Between DKA and Insulin Costs

CDC Report Understates Link Between DKA and Insulin Costs

A recent CDC report understates the relationship between DKA incidence and rising drug costs.
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