Cure InsightTreatment of Type 1 Diabetes

Are there Environmental Causes for Type 1?

Sarah Howard is the national coordinator for the Diabetes-Obesity Working Group of the Collaborative on Health and the Environment. A mom with Type 1 with a child with Type 1, she has dedicated herself to scouring research to study possible environmental factors in rising rates of Type 1 diabetes. With a master’s degree in environmental policy and education from the the University of Michigan’s School of Natural Resources and Environment, she has had eight articles and letters published in peer-reviewed science journals.

Sarah shared some of her findings with Insulin Nation.

Is Type 1 diabetes all in the genes?

No, but genetics do play a role. The incidence of Type 1 diabetes has been increasing in children living in industrialized countries worldwide since the 1950s, on the order of 3% per year. That sort of increase cannot be explained by genetics alone. Certain genes, generally those linked to the immune system, are linked to Type 1 risk, and they can provide a protective effect or increase the risk. Anyone can develop this disease, even with low-risk genes—and not everyone with high-risk genes will develop the disease.

What is the role of the environment?

Type 1 researchers generally agree that the increasing incidence in Type 1 diabetes must be due to environmental factors. What those factors are, however, remains an area of active debate and research. Some of the top contenders include: viruses (either too many or too few), vitamin D deficiency, the gut microbiota, diet/nutrition (including cow’s milk or gluten), being overweight or obese, and environmental chemicals. It very well could be a combination of factors to blame, with different factors playing different roles in each person, depending on genetic make-up, and thus making it difficult to identify any root causes of the problem.

Researchers have been looking into viruses as a cause of Type 1 diabetes for over a hundred years, but conclusive proof remains elusive. A doctor first proposed that mumps could cause diabetes in 1864, and subsequent doctors also noticed that Type 1 diabetes peaks coincided with mumps outbreaks. There is good scientific evidence now that viruses could contribute to Type 1 diabetes development in humans (e.g., viruses can cause diabetes in lab animals; signs of viruses are present in the pancreases of people with diabetes), but some scientists still question the link. Even if certain viruses do cause diabetes in some people, the infection rates of many of these viruses have not changed much since the 1950s, and may not explain the increasing incidence of Type 1.

There is less research on environmental chemicals, but the few studies that do exist show associations between Type 1 in humans and exposure to air pollution, PCBs, and nitrate/nitrite. Some animal studies also show links with BPA, a widespread chemical used in plastics.

Despite the evidence possibly linking these and other factors to Type 1 development, there are no studies that show an effective means of preventing the condition. Few prevention trials have been done, and those that have been tried were unsuccessful.

Could environmental exposures during early life affect the chances you can develop Type 1 diabetes later in life?

Some studies say that a mother’s Vitamin D deficiency during pregnancy may increase her child’s later risk of Type 1, as could Vitamin D deficiency during infancy or childhood, while other studies find no such link. Likewise, scientists are conflicted about whether breastfeeding can sometimes be protective against Type 1. A number of researchers do, however, agree that introducing solid food to babies too early in life (before 3 months of age) is associated with an increased risk of autoimmunity or Type 1 development.

How can we learn more about the evolving body of research on this subject?

I keep track of the scientific research on this topic on my website, www.diabetesandenvironment.org. It is a lot of information on a lot of research, but worthwhile to read. Sources for the above article can be found there. Also, this fall the Collaborative on Health and the Environment (CHE) will be hosting a call, “Type 1 Diabetes and the Environment,” that will feature scientists focusing on this research. Visit CHE for more information and the date at www.healthandenvironment.org. The conversation will be archived on the site, as well.

Thanks for reading this Insulin Nation article. Want more Type 1 news? Subscribe here.

Have Type 2 diabetes or know someone who does? Try Type 2 Nation, our sister publication.

Sarah Howard and her son both have Type 1 diabetes. She works with the Collaborative on Health and Environment on their diabetes and obesity working group.

Related Articles

110 Comments

  1. After reading your blog post, I browsed your website a bit and noticed you aren’t ranking nearly as well in Google as you could be. I possess a handful of blogs myself, and I think you should take a look at “groupbuyseotoolsinfo”, just google it. You’ll find it’s a very lovely wordpress SEO tools that can bring you a lot more visitors and improve your ranking. Keep up the quality posts

  2. If you are seeking for the top service to get website visitors to your web page, i advise to use seowebsitetrafficnet. I am using it with a great result. Simply just type seowebsitetrafficnet in google.

  3. After reading your blog post, I browsed your website a bit and noticed you aren’t ranking nearly as well in Google as you could be. I possess a handful of blogs myself, and I think you should take a look at “seowebsitetrafficnettools”, just google it. You’ll find it’s a very lovely SEO tool that can bring you a lot more visitors and improve your ranking. They have more than 30+ tools only 20$. Very cheap right? Keep up the quality posts

  4. tqfnpzkuh,Thanks for ones marvelous posting! I actually enjoyed reading it, you will be a great author.I will always bookmark your blog and will wzzzlaneeq,come back from now on. I want to encourage that you continue your great writing, have a nice afternoon!

  5. llxnqjcss,Thanks for ones marvelous posting! I actually enjoyed reading it, you will be a great author.I will always bookmark your blog and will gydydhbcvcz,come back from now on. I want to encourage that you continue your great writing, have a nice afternoon!

  6. fswuzyysoq,We have a team of experts who could get you the correct settings for Bellsouth net email login through which, you can easily configure your email account with MS Outlook.

  7. uygvtyszxob,Thanks a lot for providing us with this recipe of Cranberry Brisket. I’ve been wanting to make this for a long time but I couldn’t find the right recipe. Thanks to your help here, I can now make this dish easily.

  8. verjatpchu New Yeezy,Thanks a lot for providing us with this recipe of Cranberry Brisket. I’ve been wanting to make this for a long time but I couldn’t find the right recipe. Thanks to your help here, I can now make this dish easily.

  9. Game Killer Apk Download Latest Version for Android (No Ad) … Guess not because Game killer full version app is not available on Play store.

  10. Game Killer Apk Download Latest Version for Android (No Ad) … Guess not because Game killer full version app is not available on Play store.

  11. jefletxq Yeezy Boost,A very good informative article. I’ve bookmarked your website and will be checking back in future!

  12. “At the beginning of the Yuan… a familiar name, how do you feel like you heard it, its weird.” The little boy scratched his head and muttered to himself.

  13. The look is then finalized by a black midsole with a shape that any adidas Originals fan is sure to be familiar with, as its also utilized on the adidas Falcon. Enjoy a full gallery of official images below, and expect an adidas.com release in the coming weeks for $120 USD.

  14. Email Accuracy Validation through a premium industry level software process to determine if the emails are valid and accurate. Accuracy of between 95 and 97 Bring down your bounce rate on your mass email clients and decrease penalty’s.Lower the chance of your domain address being flagged as spam.

  15. In fact, on this page, you’ll find a bevy of cartoon galleries produced by artists throughout the USA TODAY Network and from Cagle Cartoons a site that archives some 200,000 cartoons from artists worldwide. We update our galleries regularly. And we’ll try to swap them onto this page so you can enjoy the most recent additions to our collection as they come. Check back often!

  16. Having read this I thought it was extremely enlightening.
    I appreciate you finding the time and effort to put this informative article together.
    I once again find myself spending a lot of time both reading and leaving comments.

    But so what, it was still worth it!

  17. What’s Taking place i’m new to this, I stumbled upon this I’ve discovered It positively helpful and
    it has helped me out loads. I am hoping to give a
    contribution & aid other users like its aided me. Great job.

  18. Although you dont need to use a special laundry detergent for babies, sometimes these can be milder for children with sensitive skin. Just be sure to read the ingredients, and make sure the product is hypoallergenic (likely to cause fewer allergic reactions) and free of dyes and fragrances.

  19. Excellent post. I was checking continuously this blog and I’m impressed!
    Very useful information specifically the last part 🙂
    I care for such info a lot. I was looking for this particular information for a very long time.
    Thank you and best of luck.

  20. Hi to every one, the contents present at this site are
    genuinely awesome for people knowledge, well, keep up the nice work
    fellows.

  21. I absolutely love your site.. Pleasant colors & theme. Did you develop this amazing site yourself?

    Please reply back as I’m looking to create my own personal site and want to find out where you got this from or exactly what the theme is called.
    Many thanks!

  22. I just like the helpful information you supply on your articles.
    I will bookmark your weblog and test once more right
    here frequently. I’m slightly sure I’ll be informed many new stuff right right here!
    Best of luck for the following!

  23. Thanks for revealing your ideas. I’d personally also like to convey that video games have been actually evolving. Modern tools and revolutions have assisted create authentic and active games. These kind of entertainment games were not that sensible when the actual concept was first of all being experimented with. Just like other areas of technological know-how, video games too have had to advance by many many years. This is testimony to the fast continuing development of video games.

  24. Hi there to every one, for the reason that I am really eager of reading this website’s post to be updated on a regular basis. It carries pleasant stuff.|

  25. One more issue is that video gaming has become one of the all-time main forms of excitement for people spanning various ages. Kids play video games, and also adults do, too. The particular XBox 360 is amongst the favorite video games systems for those who love to have a huge variety of video games available to them, as well as who like to experiment with live with other folks all over the world. Thank you for sharing your opinions.

  26. hey there and thank you for your info – I have certainly picked up anything new from right here. I did however expertise several technical issues using this web site, since I experienced to reload the web site many times previous to I could get it to load correctly. I had been wondering if your web hosting is OK? Not that I’m complaining, but slow loading instances times will very frequently affect your placement in google and can damage your high quality score if advertising and marketing with Adwords. Anyway I am adding this RSS to my email and can look out for much more of your respective intriguing content. Ensure that you update this again soon..

  27. Such scenarios matter–and not just in the context of a possible NATO/Russia or Middle East situation,Jordan but now that Russia is set to deliver the Su-35 to China,Jordan such comparisons matter even more. There are many places where all of these lethal aircraft will overlap,Jordan making such comparisons even more timely.

  28. 215202 443543Good day. Quite cool blog!! Man .. Excellent .. Wonderful .. Ill bookmark your internet site and take the feeds additionallyI am glad to locate numerous helpful info right here within the post. Thank you for sharing.. 730597

  29. eyytma,A fascinating discussion is definitely worth comment. I do think that you ought to publish more on this topic, it may not be a taboo avdjxbvbmcp,subject but generally folks don’t talk about such subjects. To the next! All the best!!

  30. 280172 462881You will discover some fascinating points in time in this post but I do not know if I see all of them center to heart. Theres some validity but I will take hold opinion until I appear into it further. Amazing post , thanks and we want a lot far more! Added to FeedBurner too 407241

  31. What i don’t understood is in truth how you are not really a lot more smartly-liked than you
    may be right now. You’re very intelligent.
    You know therefore significantly relating to this topic, produced me for my part consider it from a lot of numerous angles.
    Its like men and women aren’t interested unless it is
    one thing to accomplish with Lady gaga! Your own stuffs great.
    All the time take care of it up!

Leave a Reply

Your email address will not be published.

Back to top button