Research
Subcutaneous Islet Transplant Provides Safer, Efficient Path for Type 1 Cure
October 13, 2020
Subcutaneous Islet Transplant Provides Safer, Efficient Path for Type 1 Cure
Islet cell transplants as a mode for curing type 1 diabetes have become a popular research focus over the past decade despite the fact that scientists have been using this procedure, with minimal success, for almost sixty years. The issues…
Are Immune-Evasive Islet Cells the Key to a Type 1 Cure?
September 29, 2020
Are Immune-Evasive Islet Cells the Key to a Type 1 Cure?
Pancreatic and islet cell transplants have been used to cure diabetes in high-risk individuals. But, due to issues with availability and risks associated with immunosuppressive drugs, these procedures are far from common. Recently, researchers at the Salk Institute have come…
Antibiotic Use Linked to Higher T1D Heart Disease Risk
September 15, 2020
Antibiotic Use Linked to Higher T1D Heart Disease Risk
Frequent bacterial infections and coronary heart disease are both common complications suffered by those living with type 1 diabetes. The relationship between these conditions has traditionally been understood to be a matter of two separate conditions caused by elevated and…
Curing Type 1 Diabetes with an ‘Inverse Vaccine’
August 25, 2020
Curing Type 1 Diabetes with an ‘Inverse Vaccine’
Recently, we covered a potential diabetes cure that uses engineered T cells to stop the destruction of beta cells in those living with type 1 diabetes. Now, another potential diabetes cure that works to stimulate the proper functioning of the…
Lancet Study Confirms Type 1s at Higher Risk for COVID-19 Death
August 20, 2020
Lancet Study Confirms Type 1s at Higher Risk for COVID-19 Death
Two months ago, preliminary data out of England appeared to indicate that people with type 1 were at a greatly increased risk for death due to COVID-19 than both the general public and those living with type 2 diabetes. Last…
Unraveling the Genetic Components of Type 1 Diabetes
August 18, 2020
Unraveling the Genetic Components of Type 1 Diabetes
In the past three years, the number of people diagnosed with type 1 diabetes has increased by 30%, according to the CDC. This sudden rise in the occurrence of the disease speaks to the complexity of its heritability. We know…
Undiagnosed T1D at Increased DKA Risk During Pandemic
August 13, 2020
Undiagnosed T1D at Increased DKA Risk During Pandemic
Disruption is the New Normal No part of our daily lives seems unaffected by the global coronavirus pandemic — schools are operating online, many businesses continue to have their employees work remotely, and most people have changed how they do…
New Ultrafast Insulin Promises Better Post-Meal Numbers
July 30, 2020
New Ultrafast Insulin Promises Better Post-Meal Numbers
Meal Bolusing Challenges One of the most frustrating and difficult aspects of managing diabetes is meal bolusing. Even when you accurately count carbs, remember to bolus 20 to 40 minutes before the meal, and account for factors like fat and…
Engineered T Cells Show Promise as Effective Preventative for Diabetes
July 21, 2020
Engineered T Cells Show Promise as Effective Preventative for Diabetes
In 2015, Dr. David Rawlings, Director of Seattle Children’s Research Institute’s Center for Immunity and Immunotherapies (bio), published a paper showing how he and his team were able to target a specific receptor on precursor immune cells to transform them…
Study Reveals Beta Cell Destruction Begins Well Before Diagnosis
July 14, 2020
Study Reveals Beta Cell Destruction Begins Well Before Diagnosis
For many of us, type 1 diabetes is a disease that materializes out of thin air. One day we feel fine, then the next, something seems off. The thirst, the constant bathroom trips, the insatiable hunger, they grow over the…
New Vaccine Targets 6 Viruses that May Cause Type 1 Diabetes
June 25, 2020
New Vaccine Targets 6 Viruses that May Cause Type 1 Diabetes
A new vaccine developed by Finnish and Swedish researchers that targets six strains of enterovirus and could have a profound impact on the rates of type 1 diabetes. The viruses in question all belong to the Coxsackie B (CVB) subgroup.…
Are Gluten-Free Diets Good for Everyone?
June 23, 2020
Are Gluten-Free Diets Good for Everyone?
People with type 1 diabetes are at an increased risk for developing a number of other autoimmune disorders, including celiac disease. In fact, while celiac occurs in the general population at a rate of about 0.5%, it is seen in…
Insulin’s Role in Vascular Damage
June 16, 2020
Insulin’s Role in Vascular Damage
Cardiovascular disease is the number one killer of people living with long term type 1 diabetes. This remains true despite huge advancements in blood sugar management technology, more effective insulins, and an increased focus on heart health. The risk of…
New Study Questions Rotavirus Vaccine Effect on T1D Development
May 21, 2020
New Study Questions Rotavirus Vaccine Effect on T1D Development
Excitement over a potential preventative treatment for type 1 diabetes reached a high last year as multiple studies showed a link between inoculation with the rotavirus vaccine and a reduced rate of T1D development in children. These studies came after…
Free Type 1 Diabetes Screening for Children Saves Lives and Aids Research
May 7, 2020
Free Type 1 Diabetes Screening for Children Saves Lives and Aids Research
As a parent living with type 1 diabetes, it is impossible for me to watch my child vacuum up a meal or gulp down a glass of water without getting worried. Even something as simple as an extra heavy diaper…
Deleting Gene in Mice Prevents T1D from Developing
May 5, 2020
Deleting Gene in Mice Prevents T1D from Developing
Researchers at the University of Wisconsin-Madison made a surprising discovery recently when they deleted the IRE1-alpha gene in mice destined to develop type 1 diabetes. Deleting this gene caused the beta cells in the mice to de-differentiate or revert to…
Possible T1D Treatment Shows Promise to Reduce COVID-19 Complications
April 28, 2020
Possible T1D Treatment Shows Promise to Reduce COVID-19 Complications
I spoke with Dr. Denise Faustman about her upcoming trial to test the effectiveness of the BCG vaccine to protect high-risk healthcare workers from COVID-19 complications Last year we had the opportunity to talk with Dr. Faustman, an Associate Professor…
Should We Be Excited About ‘Curing’ T1D in Mice?
April 23, 2020
Should We Be Excited About ‘Curing’ T1D in Mice?
You have probably already heard the exciting news out of the Washington University School of Medicine in St. Louis. Researchers there have successfully implanted stem cells in mice to ‘cure’ their diabetes. As exciting as this news seems, it is…
Why T1D Diagnosis Rates Continue to Rise Across the Globe
April 22, 2020
Why T1D Diagnosis Rates Continue to Rise Across the Globe
The prevalence of type 1 diabetes was relatively stable for much of human history until the second half of the 20th century. But something very strange began to happen around 1950. Suddenly, the rate of type 1 diabetes, especially in…
Glucagon Patch Promises to Stop Low Blood Sugars Before They Happen
April 7, 2020
Glucagon Patch Promises to Stop Low Blood Sugars Before They Happen
When it comes to managing type 1 diabetes, there is one item that is central to every aspect of the condition: Insulin. This simple, yet necessary hormone has transformed what was once a sure death sentence into a condition that…